The effect of two predictors' interaction on short- and long-term treatment outcomes of schizophrenia
To monitor the effect of interaction of duration of untreated psychosis (DUP) and expressed emotion (EE) on treatment outcomes in schizophrenia. 56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the s...
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| Veröffentlicht in: | Psychiatria polska 2013-01, Vol.47 (5), p.775-786 |
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| container_title | Psychiatria polska |
| container_volume | 47 |
| creator | Cechnicki, Andrzej Bielańska, Anna Daren, Artur Wroński, Konrad Kalisz, Aneta Bładziński, Piotr Pilecki, Maciej Wojciech |
| description | To monitor the effect of interaction of duration of untreated psychosis (DUP) and expressed emotion (EE) on treatment outcomes in schizophrenia.
56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the severity of symptoms were assessed at index hospitalization and at 3, 7 and 12-year follow-ups.
No correlation was found between DUP and EE measured at index hospitalization. Over the 12-year period the number of rehospitalizations for individuals with short DUP and low EE did not increase, as opposed to those with short DUP and with high EE. In the group with long DUP, the number of rehospitalizations increased irrespectively of EE level. The positive syndrome in the group with short DUP and high EE was less severe than in individuals with long DUP and high EE. Analogous differences appeared in the group with low EE.
1) No correlation was found between DUP and EE at index hospitalization. 2) Number of rehospitalizations and intensity of positive symptoms proved to be associated over time with the interaction of DUP and EE. 3) Long-time observation and multiple assessments allow to obtain more reliable results. |
| doi_str_mv | 10.12740/pp/18215 |
| format | Article |
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56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the severity of symptoms were assessed at index hospitalization and at 3, 7 and 12-year follow-ups.
No correlation was found between DUP and EE measured at index hospitalization. Over the 12-year period the number of rehospitalizations for individuals with short DUP and low EE did not increase, as opposed to those with short DUP and with high EE. In the group with long DUP, the number of rehospitalizations increased irrespectively of EE level. The positive syndrome in the group with short DUP and high EE was less severe than in individuals with long DUP and high EE. Analogous differences appeared in the group with low EE.
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56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the severity of symptoms were assessed at index hospitalization and at 3, 7 and 12-year follow-ups.
No correlation was found between DUP and EE measured at index hospitalization. Over the 12-year period the number of rehospitalizations for individuals with short DUP and low EE did not increase, as opposed to those with short DUP and with high EE. In the group with long DUP, the number of rehospitalizations increased irrespectively of EE level. The positive syndrome in the group with short DUP and high EE was less severe than in individuals with long DUP and high EE. Analogous differences appeared in the group with low EE.
1) No correlation was found between DUP and EE at index hospitalization. 2) Number of rehospitalizations and intensity of positive symptoms proved to be associated over time with the interaction of DUP and EE. 3) Long-time observation and multiple assessments allow to obtain more reliable results.</description><subject>Adult</subject><subject>Comorbidity</subject><subject>Disease Progression</subject><subject>Expressed Emotion</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Outcome Assessment (Health Care)</subject><subject>Prognosis</subject><subject>Psychotic Disorders - epidemiology</subject><subject>Psychotic Disorders - therapy</subject><subject>Schizophrenia - epidemiology</subject><subject>Schizophrenia - therapy</subject><subject>Schizophrenic Psychology</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0033-2674</issn><issn>2391-5854</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1LAzEQQIMotlYP_gHJTT2szefu5ijFLyjYQ-9Lmkzcle5mTbKI_nrXtgoDc5jHY3gIXVJyR1khyLzv57RkVB6hKeOKZrKU4hhNCeE8Y3khJugsxndCZJGT8hRNmCSUMpZPEaxrwOAcmIS9w-nT4z6AbUzyIV7jpksQtEmN7_A4sfYhZVh3Fm9995aNxxanADq10I2CIRnfQvw1RVM3376vA3SNPkcnTm8jXBz2DK0fH9aL52z5-vSyuF9mhjOSMi6sI8IqbqiSlgpbkFwLLpUYP-eKFVKXdJMXUjnBCUilDVOUSkpcmReWz9DNXtsH_zFATFXbRAPbre7AD7GiUogxVyHkiN7uURN8jAFc1Yem1eGroqTaRa1Wq2oXdWSvDtph04L9J_8q8h8uQXDz</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Cechnicki, Andrzej</creator><creator>Bielańska, Anna</creator><creator>Daren, Artur</creator><creator>Wroński, Konrad</creator><creator>Kalisz, Aneta</creator><creator>Bładziński, Piotr</creator><creator>Pilecki, Maciej Wojciech</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130101</creationdate><title>The effect of two predictors' interaction on short- and long-term treatment outcomes of schizophrenia</title><author>Cechnicki, Andrzej ; Bielańska, Anna ; Daren, Artur ; Wroński, Konrad ; Kalisz, Aneta ; Bładziński, Piotr ; Pilecki, Maciej Wojciech</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-34df04d93c195d14d706a4359405739275a81b6759f430e59ac2911510f867d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; pol</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Comorbidity</topic><topic>Disease Progression</topic><topic>Expressed Emotion</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Outcome Assessment (Health Care)</topic><topic>Prognosis</topic><topic>Psychotic Disorders - epidemiology</topic><topic>Psychotic Disorders - therapy</topic><topic>Schizophrenia - epidemiology</topic><topic>Schizophrenia - therapy</topic><topic>Schizophrenic Psychology</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cechnicki, Andrzej</creatorcontrib><creatorcontrib>Bielańska, Anna</creatorcontrib><creatorcontrib>Daren, Artur</creatorcontrib><creatorcontrib>Wroński, Konrad</creatorcontrib><creatorcontrib>Kalisz, Aneta</creatorcontrib><creatorcontrib>Bładziński, Piotr</creatorcontrib><creatorcontrib>Pilecki, Maciej Wojciech</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatria polska</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cechnicki, Andrzej</au><au>Bielańska, Anna</au><au>Daren, Artur</au><au>Wroński, Konrad</au><au>Kalisz, Aneta</au><au>Bładziński, Piotr</au><au>Pilecki, Maciej Wojciech</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of two predictors' interaction on short- and long-term treatment outcomes of schizophrenia</atitle><jtitle>Psychiatria polska</jtitle><addtitle>Psychiatr Pol</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>47</volume><issue>5</issue><spage>775</spage><epage>786</epage><pages>775-786</pages><issn>0033-2674</issn><eissn>2391-5854</eissn><abstract>To monitor the effect of interaction of duration of untreated psychosis (DUP) and expressed emotion (EE) on treatment outcomes in schizophrenia.
56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the severity of symptoms were assessed at index hospitalization and at 3, 7 and 12-year follow-ups.
No correlation was found between DUP and EE measured at index hospitalization. Over the 12-year period the number of rehospitalizations for individuals with short DUP and low EE did not increase, as opposed to those with short DUP and with high EE. In the group with long DUP, the number of rehospitalizations increased irrespectively of EE level. The positive syndrome in the group with short DUP and high EE was less severe than in individuals with long DUP and high EE. Analogous differences appeared in the group with low EE.
1) No correlation was found between DUP and EE at index hospitalization. 2) Number of rehospitalizations and intensity of positive symptoms proved to be associated over time with the interaction of DUP and EE. 3) Long-time observation and multiple assessments allow to obtain more reliable results.</abstract><cop>Poland</cop><pmid>25011226</pmid><doi>10.12740/pp/18215</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng ; pol |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Comorbidity Disease Progression Expressed Emotion Female Follow-Up Studies Hospitalization - statistics & numerical data Humans Male Middle Aged Outcome Assessment (Health Care) Prognosis Psychotic Disorders - epidemiology Psychotic Disorders - therapy Schizophrenia - epidemiology Schizophrenia - therapy Schizophrenic Psychology Treatment Outcome Young Adult |
| title | The effect of two predictors' interaction on short- and long-term treatment outcomes of schizophrenia |
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