Megadose stem cell administration as a route to mixed chimerism

To discuss recent innovations for the application of mismatched haploidentical hematopoietic stem cell transplantation as a means to achieve immune tolerance prior to allograft transplantation. We highlight the advantages of utilizing novel 'veto' cells, to facilitate induction of mixed ch...

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Veröffentlicht in:	Current opinion in organ transplantation 2014-08, Vol.19 (4), p.334-341
Hauptverfasser:	Or-Geva, Noga, Reisner, Yair
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chimerism Graft Rejection - genetics Graft vs Host Disease - genetics Graft vs Host Disease - immunology Hematopoietic Stem Cell Transplantation - methods Humans Immune Tolerance - genetics Immune Tolerance - immunology T-Lymphocytes - immunology
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