Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents
Otomycosis as a kind of external otitis can be caused by various species of fungi. To use the appropriate treatment, it is necessary to identify the causal agent of otomycosis. The aim of this study was to determine the pathogens that caused otomycosis and also the efficacy of different antifungal a...
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Veröffentlicht in: | European archives of oto-rhino-laryngology 2014-05, Vol.271 (5), p.953-957 |
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creator | Nemati, Shadman Hassanzadeh, Rasool Khajeh Jahromi, Sina Delkhosh Nasrollah Abadi, Azimeh |
description | Otomycosis as a kind of external otitis can be caused by various species of fungi. To use the appropriate treatment, it is necessary to identify the causal agent of otomycosis. The aim of this study was to determine the pathogens that caused otomycosis and also the efficacy of different antifungal agents. 100 patients with diagnosis of otomycosis/otitis extern were entered in this study. Bacterial culture was performed by eosin methylene blue agar, blood agar; and Sabouraud dextrose agar was used to culture the fungal agents. Minimum inhibitory concentration test also was performed to determine the efficacy of Clotrimazole, Fluconazole, Ketoconazole and Nystatin on the fungal pathogens. Otomycosis was confirmed in 43 % of patients by positive culture. The most prevalent fungal pathogen was
Aspergillus niger
which was sensitive to Clotrimazole, Fluconazole, Ketoconazole.
Candida albicans
was sensitive to all drugs, in which, the most sensitivity was due to fluconazole. The most frequent fungal pathogen in our otomycosis cases is
A. niger
, and most of fungi that caused otomycosis are sensitive to clotrimazole. |
doi_str_mv | 10.1007/s00405-013-2486-0 |
format | Article |
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Aspergillus niger
which was sensitive to Clotrimazole, Fluconazole, Ketoconazole.
Candida albicans
was sensitive to all drugs, in which, the most sensitivity was due to fluconazole. The most frequent fungal pathogen in our otomycosis cases is
A. niger
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Aspergillus niger
which was sensitive to Clotrimazole, Fluconazole, Ketoconazole.
Candida albicans
was sensitive to all drugs, in which, the most sensitivity was due to fluconazole. The most frequent fungal pathogen in our otomycosis cases is
A. niger
, and most of fungi that caused otomycosis are sensitive to clotrimazole.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Aspergillosis - drug therapy</subject><subject>Aspergillosis - epidemiology</subject><subject>Aspergillus fumigatus - drug effects</subject><subject>Aspergillus niger</subject><subject>Candida albicans</subject><subject>Candidiasis - drug therapy</subject><subject>Candidiasis - epidemiology</subject><subject>Child</subject><subject>Climate</subject><subject>Cross-Sectional Studies</subject><subject>Developing Countries</subject><subject>Drug Resistance, Fungal</subject><subject>Female</subject><subject>Head and Neck Surgery</subject><subject>Humans</subject><subject>Iran</subject><subject>Lung Diseases, Fungal - drug therapy</subject><subject>Lung Diseases, Fungal - epidemiology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Microbial Sensitivity Tests</subject><subject>Middle Aged</subject><subject>Neurosurgery</subject><subject>Otology</subject><subject>Otomycosis - drug therapy</subject><subject>Otomycosis - epidemiology</subject><subject>Otomycosis - microbiology</subject><subject>Otorhinolaryngology</subject><subject>Risk Factors</subject><subject>Young Adult</subject><issn>0937-4477</issn><issn>1434-4726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkDtPwzAYRS0EoqXwA1iQR5aA30nYEOJRqVIXOluO7bSpGrvYztB_j6sURsRk6fO597MPALcYPWCEyseIEEO8QJgWhFWiQGdgihllBSuJOAdTVNOyYKwsJ-Aqxi1CiLOaXoIJobzmAvMpWC2T7w_axy7CzsG0sdD5kDbQt3AelHuC2ve9d3Cv0savrYtQOQODzYGknLYw-TxJXTu4tdpBlZEUr8FFq3bR3pzOGVi9vX6-fBSL5fv85XlRaFqWqTCGVbRq6iq_RzFrNCKECCu0YJRog4VlDTaCmrauGkNtwyrLm5bn36m6QYTOwP3Yuw_-a7Axyb6L2u52ylk_RIk5Y9lOXdF_oJjlrbXgGcUjqoOPMdhW7kPXq3CQGMmjeDmKl7laHsVLlDN3p_qh6a35TfyYzgAZgZiv3NoGufVDcNnOH63fFt2Nog</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Nemati, Shadman</creator><creator>Hassanzadeh, Rasool</creator><creator>Khajeh Jahromi, Sina</creator><creator>Delkhosh Nasrollah Abadi, Azimeh</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope></search><sort><creationdate>20140501</creationdate><title>Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents</title><author>Nemati, Shadman ; 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To use the appropriate treatment, it is necessary to identify the causal agent of otomycosis. The aim of this study was to determine the pathogens that caused otomycosis and also the efficacy of different antifungal agents. 100 patients with diagnosis of otomycosis/otitis extern were entered in this study. Bacterial culture was performed by eosin methylene blue agar, blood agar; and Sabouraud dextrose agar was used to culture the fungal agents. Minimum inhibitory concentration test also was performed to determine the efficacy of Clotrimazole, Fluconazole, Ketoconazole and Nystatin on the fungal pathogens. Otomycosis was confirmed in 43 % of patients by positive culture. The most prevalent fungal pathogen was
Aspergillus niger
which was sensitive to Clotrimazole, Fluconazole, Ketoconazole.
Candida albicans
was sensitive to all drugs, in which, the most sensitivity was due to fluconazole. The most frequent fungal pathogen in our otomycosis cases is
A. niger
, and most of fungi that caused otomycosis are sensitive to clotrimazole.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23595615</pmid><doi>10.1007/s00405-013-2486-0</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Antifungal Agents - therapeutic use Aspergillosis - drug therapy Aspergillosis - epidemiology Aspergillus fumigatus - drug effects Aspergillus niger Candida albicans Candidiasis - drug therapy Candidiasis - epidemiology Child Climate Cross-Sectional Studies Developing Countries Drug Resistance, Fungal Female Head and Neck Surgery Humans Iran Lung Diseases, Fungal - drug therapy Lung Diseases, Fungal - epidemiology Male Medicine Medicine & Public Health Microbial Sensitivity Tests Middle Aged Neurosurgery Otology Otomycosis - drug therapy Otomycosis - epidemiology Otomycosis - microbiology Otorhinolaryngology Risk Factors Young Adult |
title | Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents |
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