Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents

Otomycosis as a kind of external otitis can be caused by various species of fungi. To use the appropriate treatment, it is necessary to identify the causal agent of otomycosis. The aim of this study was to determine the pathogens that caused otomycosis and also the efficacy of different antifungal a...

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Veröffentlicht in:European archives of oto-rhino-laryngology 2014-05, Vol.271 (5), p.953-957
Hauptverfasser: Nemati, Shadman, Hassanzadeh, Rasool, Khajeh Jahromi, Sina, Delkhosh Nasrollah Abadi, Azimeh
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container_title European archives of oto-rhino-laryngology
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creator Nemati, Shadman
Hassanzadeh, Rasool
Khajeh Jahromi, Sina
Delkhosh Nasrollah Abadi, Azimeh
description Otomycosis as a kind of external otitis can be caused by various species of fungi. To use the appropriate treatment, it is necessary to identify the causal agent of otomycosis. The aim of this study was to determine the pathogens that caused otomycosis and also the efficacy of different antifungal agents. 100 patients with diagnosis of otomycosis/otitis extern were entered in this study. Bacterial culture was performed by eosin methylene blue agar, blood agar; and Sabouraud dextrose agar was used to culture the fungal agents. Minimum inhibitory concentration test also was performed to determine the efficacy of Clotrimazole, Fluconazole, Ketoconazole and Nystatin on the fungal pathogens. Otomycosis was confirmed in 43 % of patients by positive culture. The most prevalent fungal pathogen was Aspergillus niger which was sensitive to Clotrimazole, Fluconazole, Ketoconazole. Candida albicans was sensitive to all drugs, in which, the most sensitivity was due to fluconazole. The most frequent fungal pathogen in our otomycosis cases is A. niger , and most of fungi that caused otomycosis are sensitive to clotrimazole.
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subjects Adolescent
Adult
Aged
Aged, 80 and over
Antifungal Agents - therapeutic use
Aspergillosis - drug therapy
Aspergillosis - epidemiology
Aspergillus fumigatus - drug effects
Aspergillus niger
Candida albicans
Candidiasis - drug therapy
Candidiasis - epidemiology
Child
Climate
Cross-Sectional Studies
Developing Countries
Drug Resistance, Fungal
Female
Head and Neck Surgery
Humans
Iran
Lung Diseases, Fungal - drug therapy
Lung Diseases, Fungal - epidemiology
Male
Medicine
Medicine & Public Health
Microbial Sensitivity Tests
Middle Aged
Neurosurgery
Otology
Otomycosis - drug therapy
Otomycosis - epidemiology
Otomycosis - microbiology
Otorhinolaryngology
Risk Factors
Young Adult
title Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents
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