Changes in Neuron-Specific Enolase are More Suitable Than Its Absolute Serum Levels for the Prediction of Neurologic Outcome in Hypothermia-Treated Patients with Out-of-Hospital Cardiac Arrest

Background To determine neurologic outcome in patients with out-of-hospital cardiac arrest (OHCA) and treatment with mild therapeutic hypothermia (MTH). Methods Seventy-three consecutive OHCA patients treated with MTH were retrospectively analyzed. Serum neuron-specific enolase (NSE) was measured 24...

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Veröffentlicht in:	Neurocritical care 2014-06, Vol.20 (3), p.358-366
Hauptverfasser:	Huntgeburth, Michael, Adler, Christoph, Rosenkranz, Stephan, Zobel, Carsten, Haupt, Walter F., Dohmen, Christian, Reuter, Hannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anesthesia Biomarkers - blood Cardiac arrest Cardiac arrhythmia Cardiopulmonary resuscitation Catheters Coma Coma - diagnosis Coma - therapy Contraindications Cooling CPR Critical Care Critical Care Medicine Disability Emergency services Enzymes Evoked Potentials Female Hospitals Humans Hypothermia Hypothermia, Induced Intensive Intensive care Internal Medicine Male Medical prognosis Medicine Medicine & Public Health Middle Aged Neurologic Examination Neurology Original Article Out-of-Hospital Cardiac Arrest - diagnosis Out-of-Hospital Cardiac Arrest - therapy Patients Phosphopyruvate Hydratase - blood Physiology Predictive Value of Tests Recovery of Function Retrospective Studies ROC Curve Sensitivity and Specificity Standard of care Treatment Outcome Ventilators
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