Synthesis, insecticidal, and fungicidal screening of some new quinoline derivatives
This paper describes the synthesis of a series of quinolines graphted with hydrazones, pyrazoles, pyridazine, phthalazine, triazepinone, semicarbazide, and thiomorpholide moieties and four metal complexes. These derivatives were screened against Fusarium oxysporum and the red palm weevil (RPW) Rhync...
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Veröffentlicht in: | Russian journal of bioorganic chemistry 2014-03, Vol.40 (2), p.214-227 |
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creator | Aly, M. R. E. Ibrahim, M. M. Okael, A. M. Gherbawy, Y. A. M. H. |
description | This paper describes the synthesis of a series of quinolines graphted with hydrazones, pyrazoles, pyridazine, phthalazine, triazepinone, semicarbazide, and thiomorpholide moieties and four metal complexes. These derivatives were screened against
Fusarium oxysporum
and the red palm weevil (RPW)
Rhynchophorus ferrugineus
Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon complexation with Zn
2+
ions. |
doi_str_mv | 10.1134/S1068162014020022 |
format | Article |
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Fusarium oxysporum
and the red palm weevil (RPW)
Rhynchophorus ferrugineus
Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon complexation with Zn
2+
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Fusarium oxysporum
and the red palm weevil (RPW)
Rhynchophorus ferrugineus
Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon complexation with Zn
2+
ions.</description><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bioorganic Chemistry</subject><subject>Curculionidae</subject><subject>Fusarium oxysporum</subject><subject>Life Sciences</subject><subject>Organic Chemistry</subject><subject>Rhynchophorus ferrugineus</subject><issn>1068-1620</issn><issn>1608-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp9kE9Lw0AQxRdRsFY_gLc9emh0ZrPZpEcp_oOChyp4C8lmUrekm3YnUfrtTYk3wdPM8Htv4D0hrhFuEWN9t0IwGRoFqEEBKHUiJmggi-IYPk6HfcDRkZ-LC-YNAAIk2USsVgfffRI7nknnmWznrKuKZiYLX8m69-vxlmwDkXd-Ldtacrsl6elb7nvn28Z5khUF91V07ov4UpzVRcN09Tun4v3x4W3xHC1fn14W98vIxgq7iGqNRElazOdoIannWqXW0BxLS1lKRsNAKiCdqJJiSipdpqkutakUlVDH8VTcjH93od33xF2-dWypaQpPbc85JloDojHJIMVRakPLHKjOd8Fti3DIEfJjgfmfAgePGj08aP2aQr5p--CHRP-YfgBst3LT</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Aly, M. R. E.</creator><creator>Ibrahim, M. M.</creator><creator>Okael, A. M.</creator><creator>Gherbawy, Y. A. M. H.</creator><general>Pleiades Publishing</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20140301</creationdate><title>Synthesis, insecticidal, and fungicidal screening of some new quinoline derivatives</title><author>Aly, M. R. E. ; Ibrahim, M. M. ; Okael, A. M. ; Gherbawy, Y. A. M. H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-ef41ee57a991c05f9427c6e91bce87e640a99d0e452be3e5d4b774b46d2eb0f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bioorganic Chemistry</topic><topic>Curculionidae</topic><topic>Fusarium oxysporum</topic><topic>Life Sciences</topic><topic>Organic Chemistry</topic><topic>Rhynchophorus ferrugineus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aly, M. R. E.</creatorcontrib><creatorcontrib>Ibrahim, M. M.</creatorcontrib><creatorcontrib>Okael, A. M.</creatorcontrib><creatorcontrib>Gherbawy, Y. A. M. H.</creatorcontrib><collection>CrossRef</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Russian journal of bioorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aly, M. R. E.</au><au>Ibrahim, M. M.</au><au>Okael, A. M.</au><au>Gherbawy, Y. A. M. H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis, insecticidal, and fungicidal screening of some new quinoline derivatives</atitle><jtitle>Russian journal of bioorganic chemistry</jtitle><stitle>Russ J Bioorg Chem</stitle><date>2014-03-01</date><risdate>2014</risdate><volume>40</volume><issue>2</issue><spage>214</spage><epage>227</epage><pages>214-227</pages><issn>1068-1620</issn><eissn>1608-330X</eissn><abstract>This paper describes the synthesis of a series of quinolines graphted with hydrazones, pyrazoles, pyridazine, phthalazine, triazepinone, semicarbazide, and thiomorpholide moieties and four metal complexes. These derivatives were screened against
Fusarium oxysporum
and the red palm weevil (RPW)
Rhynchophorus ferrugineus
Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon complexation with Zn
2+
ions.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1068162014020022</doi><tpages>14</tpages></addata></record> |
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subjects | Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Curculionidae Fusarium oxysporum Life Sciences Organic Chemistry Rhynchophorus ferrugineus |
title | Synthesis, insecticidal, and fungicidal screening of some new quinoline derivatives |
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