Investigation into in vitro and in vivo models using intestinal epithelial IPEC‐J2 cells and Caenorhabditis elegans for selecting probiotic candidates to control porcine enterotoxigenic Escherichia coli

AIMS: To identify a fast, economic and reliable method for preselecting lactic acid‐producing bacterial (LAB) isolates to control enterotoxigenic Escherichia coli (ETEC). METHODS AND RESULTS: Two assays with porcine intestinal epithelial IPEC‐J2 cells or Caenorhabditis elegans for selecting effectiv...

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Veröffentlicht in:	Journal of applied microbiology 2014-07, Vol.117 (1), p.217-226
Hauptverfasser:	Zhou, M, Zhu, J, Yu, H, Yin, X, Sabour, P.M, Zhao, L, Chen, W, Gong, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiosis Antimicrobial Cationic Peptides - agonists Antimicrobial Cationic Peptides - biosynthesis antimicrobial peptides Biological and medical sciences Caenorhabditis elegans Caenorhabditis elegans - drug effects Caenorhabditis elegans - microbiology Cell Line death E coli enterotoxigenic Escherichia coli Enterotoxigenic Escherichia coli - drug effects Enterotoxigenic Escherichia coli - growth & development enterotoxins Enterotoxins - antagonists & inhibitors Enterotoxins - biosynthesis Epithelial Cells - drug effects Epithelial Cells - microbiology Escherichia coli Escherichia coli Infections - diet therapy Escherichia coli Infections - microbiology Escherichia coli Infections - veterinary Fundamental and applied biological sciences. Psychology Gene expression genes interleukin-10 Interleukin-10 - agonists Interleukin-10 - metabolism interleukin-8 Interleukin-8 - antagonists & inhibitors Interleukin-8 - metabolism Intestines - drug effects Intestines - microbiology IPEC‐J2 lactic acid‐producing bacteria Lactobacillus reuteri Lactobacillus reuteri - physiology Microbiology models for selection Models, Biological Nematodes Probiotics Probiotics - pharmacology screening Swine Swine Diseases - diet therapy Swine Diseases - microbiology
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