Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity: e1003433

Since the discovery of tumour initiating cells (TICs) in solid tumours, studies focussing on their role in cancer initiation and progression have abounded. The biological interrogation of these cells continues to yield volumes of information on their pro-tumourigenic behaviour, but actionable genera...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PLoS computational biology 2014-01, Vol.10 (1)
Hauptverfasser:	Scott, Jacob G, Hjelmeland, Anita B, Chinnaiyan, Prakash, Anderson, Alexander RA, Basanta, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavior Cancer Cancer therapies Cell division Homeostasis Hypotheses Stem cells Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!