Functional polymorphisms in COMT and SLC6A4 genes influence the prognosis of patients with medication overuse headache after withdrawal therapy

Background and purpose It is currently unknown if common genetic variants influence the prognosis of patients with medication overuse headache (MOH). Here the role of two common single nucleotide polymorphisms in the COMT gene (rs4680 and rs6269), as well as the STin2 variable number tandem repeat (...

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Veröffentlicht in:	European journal of neurology 2014-07, Vol.21 (7), p.989-995
Hauptverfasser:	Cargnin, S., Viana, M., Ghiotto, N., Bianchi, M., Sances, G., Tassorelli, C., Nappi, G., Canonico, P. L., Genazzani, A. A., Terrazzino, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Catechol O-Methyltransferase - genetics COMT detoxification Genetic Predisposition to Disease Headache Disorders, Secondary - chemically induced Headache Disorders, Secondary - diagnosis Headache Disorders, Secondary - genetics Humans medication overuse headache Polymorphism, Genetic polymorphisms Prognosis Recurrence relapse Serotonin Plasma Membrane Transport Proteins - genetics SLC6A4
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