Molecular basis of biodegradation of chloroaromatic compounds

Chlorinated aromatic hydrocarbons are widely used in industry and agriculture, and comprise the bulk of environmental pollutants. Although simple aromatic compounds are biodegradable by a variety of degradative pathways, their halogenated counterparts are more resistant to bacterial attack and often...

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Veröffentlicht in:Acta biotechnologica 1989, Vol.9 (4), p.301-316
Hauptverfasser: Sangodkar, U. M. X., Aldrich, T. L., Haugland, R. A., Johnson, J., Rothmel, R. K., Chapman, P. J., Chakrabarty, A. M.
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container_end_page 316
container_issue 4
container_start_page 301
container_title Acta biotechnologica
container_volume 9
creator Sangodkar, U. M. X.
Aldrich, T. L.
Haugland, R. A.
Johnson, J.
Rothmel, R. K.
Chapman, P. J.
Chakrabarty, A. M.
description Chlorinated aromatic hydrocarbons are widely used in industry and agriculture, and comprise the bulk of environmental pollutants. Although simple aromatic compounds are biodegradable by a variety of degradative pathways, their halogenated counterparts are more resistant to bacterial attack and often necessitate evolution of novel pathways. An understanding of such evolutionary processes is essential for developing genetically improved strains capable of mineralizing highly chlorinated compounds. This article provides an overview of the genetic aspects of dissimilation of chloroaromatic compounds and discusses the potential of gene manipulation to promote enhanced evolution of the degradative pathways.
doi_str_mv 10.1002/abio.370090402
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source Wiley Online Library Journals Frontfile Complete
subjects aromatic compounds
Bacteriology
biodegradation
Biological and medical sciences
Biotechnology
cleaning process
Environment and pollution
Fundamental and applied biological sciences. Psychology
Industrial applications and implications. Economical aspects
Metabolism. Enzymes
Microbiology
Miscellaneous
pollution clean-up
pollution control
title Molecular basis of biodegradation of chloroaromatic compounds
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