Stability of 1% voriconazole solution in a constant‐rate infusion pump for topical ocular delivery to horses

OBJECTIVE: To establish the effect of storage in a constant‐rate infusion (CRI) pump on the sterility and stability of voriconazole 1% solution. PROCEDURE: Nine vials of voriconazole (Vfend® I.V.) 1% solution were prepared. Approximately half of each solution was used to prime a commercially availab...

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Veröffentlicht in:	Veterinary ophthalmology 2014-07, Vol.17 (s1), p.82-89
Hauptverfasser:	Smith, Kathryn M, Maxwell, Lara, Gull, Tamara, Payton, Mark E, Gilmour, Margi A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antifungal Agents - administration & dosage Antifungal Agents - therapeutic use constant-rate infusion pump cornea Drug Stability Drug Storage - methods equine Eye Infections, Fungal - drug therapy Eye Infections, Fungal - veterinary fungi glass Horse Diseases - drug therapy Horses Infusion Pumps - veterinary liquid chromatography pumps stability storage time subpalpebral lavage temperature voriconazole Voriconazole - administration & dosage Voriconazole - therapeutic use
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