Phorbol esters inhibit chondrogenesis in limb mesenchyme by mechanisms independent of PGE sub(2) or cyclic AMP

Effects of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) on chondrogenesis and concentrations of prostaglandin E sub(2) (PGE sub(2)) and cyclic AMP (cAMP) were investigated in micromass cultures of chick limb mesenchyme derived from the distal tip of stage 25 limb buds. TPA completely...

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Veröffentlicht in:Experimental cell research 1989-01, Vol.185 (2), p.541-545
Hauptverfasser: Biddulph, D M, Dozier, M M
Format: Artikel
Sprache:eng
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