EXOGENOUS ESTROGENS AND BREAST CANCER

Rates of breast cancer at Group Health Cooperative of Puget Sound, Seattle, Washington, a health maintenance organization, remained stable from 1972–1979 in women aged 30–44 years and in women aged 55–64 years, despite the fact that the frequency of use of estrogen-containing drugs has varied substa...

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Veröffentlicht in:American journal of epidemiology 1981-11, Vol.114 (5), p.710-713
Hauptverfasser: LAWSON, DAVID H., JICK, HERSHEL, HUNTER, JUDITH R., MADSEN, SUE
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container_end_page 713
container_issue 5
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container_title American journal of epidemiology
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creator LAWSON, DAVID H.
JICK, HERSHEL
HUNTER, JUDITH R.
MADSEN, SUE
description Rates of breast cancer at Group Health Cooperative of Puget Sound, Seattle, Washington, a health maintenance organization, remained stable from 1972–1979 in women aged 30–44 years and in women aged 55–64 years, despite the fact that the frequency of use of estrogen-containing drugs has varied substantially. By contrast, rates of breast cancer in women aged 45–54 years appear to have fallen since 1977 in association with a substantial fall in estrogen use in women of this age group. The results are consistent with an etlologic role for current exogenous estrogen in breast cancer in middle-aged women.
doi_str_mv 10.1093/oxfordjournals.aje.a113242
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subjects Adult
Age Factors
breast neoplasms
Breast Neoplasms - chemically induced
Breast Neoplasms - epidemiology
Drug Utilization
estrogens
Estrogens - adverse effects
Female
Humans
Middle Aged
Risk
Time Factors
Washington
title EXOGENOUS ESTROGENS AND BREAST CANCER
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