EXOGENOUS ESTROGENS AND BREAST CANCER
Rates of breast cancer at Group Health Cooperative of Puget Sound, Seattle, Washington, a health maintenance organization, remained stable from 1972–1979 in women aged 30–44 years and in women aged 55–64 years, despite the fact that the frequency of use of estrogen-containing drugs has varied substa...
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Veröffentlicht in: | American journal of epidemiology 1981-11, Vol.114 (5), p.710-713 |
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creator | LAWSON, DAVID H. JICK, HERSHEL HUNTER, JUDITH R. MADSEN, SUE |
description | Rates of breast cancer at Group Health Cooperative of Puget Sound, Seattle, Washington, a health maintenance organization, remained stable from 1972–1979 in women aged 30–44 years and in women aged 55–64 years, despite the fact that the frequency of use of estrogen-containing drugs has varied substantially. By contrast, rates of breast cancer in women aged 45–54 years appear to have fallen since 1977 in association with a substantial fall in estrogen use in women of this age group. The results are consistent with an etlologic role for current exogenous estrogen in breast cancer in middle-aged women. |
doi_str_mv | 10.1093/oxfordjournals.aje.a113242 |
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By contrast, rates of breast cancer in women aged 45–54 years appear to have fallen since 1977 in association with a substantial fall in estrogen use in women of this age group. The results are consistent with an etlologic role for current exogenous estrogen in breast cancer in middle-aged women.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>DOI: 10.1093/oxfordjournals.aje.a113242</identifier><identifier>PMID: 7304599</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Adult ; Age Factors ; breast neoplasms ; Breast Neoplasms - chemically induced ; Breast Neoplasms - epidemiology ; Drug Utilization ; estrogens ; Estrogens - adverse effects ; Female ; Humans ; Middle Aged ; Risk ; Time Factors ; Washington</subject><ispartof>American journal of epidemiology, 1981-11, Vol.114 (5), p.710-713</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-2be575a62e43eb6e4a19a5c314f678b483df9fb46333d68f0977ee5451864c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27869,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7304599$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LAWSON, DAVID H.</creatorcontrib><creatorcontrib>JICK, HERSHEL</creatorcontrib><creatorcontrib>HUNTER, JUDITH R.</creatorcontrib><creatorcontrib>MADSEN, SUE</creatorcontrib><title>EXOGENOUS ESTROGENS AND BREAST CANCER</title><title>American journal of epidemiology</title><addtitle>Am J Epidemiol</addtitle><description>Rates of breast cancer at Group Health Cooperative of Puget Sound, Seattle, Washington, a health maintenance organization, remained stable from 1972–1979 in women aged 30–44 years and in women aged 55–64 years, despite the fact that the frequency of use of estrogen-containing drugs has varied substantially. By contrast, rates of breast cancer in women aged 45–54 years appear to have fallen since 1977 in association with a substantial fall in estrogen use in women of this age group. The results are consistent with an etlologic role for current exogenous estrogen in breast cancer in middle-aged women.</description><subject>Adult</subject><subject>Age Factors</subject><subject>breast neoplasms</subject><subject>Breast Neoplasms - chemically induced</subject><subject>Breast Neoplasms - epidemiology</subject><subject>Drug Utilization</subject><subject>estrogens</subject><subject>Estrogens - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Risk</subject><subject>Time Factors</subject><subject>Washington</subject><issn>0002-9262</issn><issn>1476-6256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNpdkN1Kw0AQRhdRaq0-glAUvUvd2b9kvYsxbYWSShKheLNs0g20tqZmG6hvb0pjQa9m4DvfDByEbgAPAEv6UO6Kspovy7r61Cs70Esz0ACUMHKCusBc4QjCxSnqYoyJI4kg5-jC2iXGAJLjDuq4FDMuZRfdhbPpKIymb0k_TNJ4vyd9P3ruP8Whn6T9wI-CML5EZ0XzyVy1s4eSYZgGY2cyHb0E_sTJGcDWIZnhLteCGEZNJgzTIDXPKbBCuF7GPDovZJExQSmdC6_A0nWN4YyDJ1hOe-j-cHVTlV-1sVu1XtjcrFb605S1VcAZkUBEA97-A39dKKBYCA4Ss4Z6PFB5VVpbmUJtqsVaV98KsNp7VH89qsajaj025ev2RZ2tzfxYbcU1uXPIF3ZrdsdYVx9KuNTlajx7V_HoFQ_TmKqI_gCqbX5e</recordid><startdate>198111</startdate><enddate>198111</enddate><creator>LAWSON, DAVID H.</creator><creator>JICK, HERSHEL</creator><creator>HUNTER, JUDITH R.</creator><creator>MADSEN, SUE</creator><general>Oxford University Press</general><general>School of Hygiene and Public Health of the Johns Hopkins University</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HVZBN</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>198111</creationdate><title>EXOGENOUS ESTROGENS AND BREAST CANCER</title><author>LAWSON, DAVID H. ; JICK, HERSHEL ; HUNTER, JUDITH R. ; MADSEN, SUE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-2be575a62e43eb6e4a19a5c314f678b483df9fb46333d68f0977ee5451864c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>breast neoplasms</topic><topic>Breast Neoplasms - chemically induced</topic><topic>Breast Neoplasms - epidemiology</topic><topic>Drug Utilization</topic><topic>estrogens</topic><topic>Estrogens - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Risk</topic><topic>Time Factors</topic><topic>Washington</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LAWSON, DAVID H.</creatorcontrib><creatorcontrib>JICK, HERSHEL</creatorcontrib><creatorcontrib>HUNTER, JUDITH R.</creatorcontrib><creatorcontrib>MADSEN, SUE</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Periodicals Index Online Segment 24</collection><collection>Periodicals Index Online</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - 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source | MEDLINE; Oxford University Press Archive; Periodicals Index Online |
subjects | Adult Age Factors breast neoplasms Breast Neoplasms - chemically induced Breast Neoplasms - epidemiology Drug Utilization estrogens Estrogens - adverse effects Female Humans Middle Aged Risk Time Factors Washington |
title | EXOGENOUS ESTROGENS AND BREAST CANCER |
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