Use of human papillomavirus vaccine in HIV-infected men for the prevention of anal dysplasia and cancer
There are two commercially available vaccines licensed worldwide for the prevention of cervical cancer and other human papillomavirus-associated cancers such as anal cancer. However, only two countries have implemented healthcare programs that include human papillomavirus vaccination for boys and me...
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| Veröffentlicht in: | AIDS reviews 2014-04, Vol.16 (2), p.90-100 |
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| creator | Cachay, Edward R Mathews, Wm Christopher |
| description | There are two commercially available vaccines licensed worldwide for the prevention of cervical cancer and other human papillomavirus-associated cancers such as anal cancer. However, only two countries have implemented healthcare programs that include human papillomavirus vaccination for boys and men. Although most of the human papillomavirus-related cancers in the world are attributable to cervical cancer, in developed countries anal cancer accounts for a larger proportion of human papillomavirus-related cancers. Most cases of anal cancer occur in HIV-infected men who have sex with men. In this review, we discuss the burden of human papillomavirus-related cancers in men, the most plausible immune mechanism associated with the high efficacy of the human papillomavirus vaccine, and address key issues of vaccination for HIV-infected men. Finally, we review cost-effectiveness considerations for the use of the vaccine in boys and recent guidelines for vaccination in boys, with attention to HIV-infected men. |
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| identifier | EISSN: 1698-6997 |
| ispartof | AIDS reviews, 2014-04, Vol.16 (2), p.90-100 |
| issn | 1698-6997 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Anus Diseases - immunology Anus Diseases - pathology Anus Diseases - prevention & control Cancer Vaccines - economics Cost-Benefit Analysis HIV Seropositivity - immunology HIV Seropositivity - pathology Homosexuality, Male Humans Male Papillomavirus Infections - immunology Papillomavirus Infections - pathology Papillomavirus Infections - prevention & control Papillomavirus Vaccines - economics Secondary Prevention |
| title | Use of human papillomavirus vaccine in HIV-infected men for the prevention of anal dysplasia and cancer |
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