IndividualizedPath: identifying genetic alterations contributing to the dysfunctional pathways in glioblastoma individuals

Due to the extensive complexity and high genetic heterogeneity of genetic alterations in cancer, comprehensively depicting the molecular mechanisms of cancer remains difficult. Characterizing personalized pathogenesis in cancer individuals can help to reveal new details of the complex mechanisms. In...

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Veröffentlicht in:	Molecular bioSystems 2014-01, Vol.10 (8), p.2031-2042
Hauptverfasser:	Ping, Yanyan, Zhang, Hongyi, Deng, Yulan, Wang, Li, Zhao, Hongying, Pang, Lin, Fan, Huihui, Xu, Chaohan, Li, Feng, Zhang, Yong, Gong, Yonghui, Xiao, Yun, Li, Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Computational Biology - methods Databases, Genetic DNA Copy Number Variations Gene Expression Regulation, Neoplastic Gene Regulatory Networks Glioblastoma - genetics Glioblastoma - pathology Humans Proto-Oncogene Proteins c-met - genetics Receptor, Epidermal Growth Factor - genetics Signal Transduction
Online-Zugang:	Volltext
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