Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response

Background Recently, interferon-inducible guanylate binding protein (GBP2) has been discussed as a possible control factor in tumor development, which is controlled by p53, and inhibits NF-Kappa B and Rac protein as well as expression of matrix metalloproteinase 9. However, the potential role that G...

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Veröffentlicht in:	Breast cancer (Tokyo, Japan) Japan), 2014-07, Vol.21 (4), p.491-499
Hauptverfasser:	Godoy, Patricio, Cadenas, Cristina, Hellwig, Birte, Marchan, Rosemarie, Stewart, Joanna, Reif, Raymond, Lohr, Miriam, Gehrmann, Matthias, Rahnenführer, Jörg, Schmidt, Markus, Hengstler, Jan G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anthracyclines Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological response modifiers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer Cancer Research Chemotherapy Cohort Studies Development and progression Estrogen Female Follow-Up Studies Gene Expression Profiling GTP-Binding Proteins - genetics Humans Immunoenzyme Techniques Interferon Medical research Medicine Medicine & Public Health Medicine, Experimental Metastasis Middle Aged Neoadjuvant Therapy Neoplasm Grading Neoplasm Staging Oligonucleotide Array Sequence Analysis Oncology Original Article Prognosis Protein binding Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism RNA Surgery Surgical Oncology Survival Rate T cells T-Lymphocytes - immunology Tumor proteins
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