Urinary metabolite profiling identifies novel colonic metabolites and conjugates of phenolics in healthy volunteers

SCOPE: The colonic metabolism of dietary flavonoids, phenolic acids and their phenolic metabolites is complex and many metabolites and conjugates have not yet been unambiguously identified in humans. METHODS AND RESULTS: Urine samples from nine healthy human volunteers obtained after the ingestion o...

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Veröffentlicht in:	Molecular nutrition & food research 2014-07, Vol.58 (7), p.1414-1425
Hauptverfasser:	Pimpão, Rui C, Dew, Tristan, Figueira, Maria E, McDougall, Gordon J, Stewart, Derek, Ferreira, Ricardo B, Santos, Claudia N, Williamson, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alanine Transaminase - blood Aspartate Aminotransferases - blood Berry fruits Bioavailability Biological and medical sciences biomarkers Biomarkers - urine Blood Glucose - metabolism Blueberry Plants - chemistry Body Mass Index Catechin - urine catechol Cholesterol, HDL - blood Cholesterol, LDL - blood Chromatography, Liquid Colon Colon - metabolism Conjugates Creatinine - blood Feeding. Feeding behavior Female flavonoids Fragaria - chemistry Fruit - chemistry fruit consumption Fundamental and applied biological sciences. Psychology gallic acid Gallic Acid - urine gamma-Glutamyltransferase - blood Healthy Volunteers Humans ingestion intestinal absorption Male metabolism metabolites Metabolomics Middle Aged Polyphenols - metabolism Polyphenols - urine protocatechuic acid pyrogallol Rubus - chemistry small fruits small intestine Surveys and Questionnaires Tandem Mass Spectrometry Triglycerides - blood urine vanillic acid Vertebrates: anatomy and physiology, studies on body, several organs or systems volunteers Young Adult
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