Lanthanide-Chelating Carbohydrate Conjugates Are Useful Tools To Characterize Carbohydrate Conformation in Solution and Sensitive Sensors to Detect Carbohydrate–Protein Interactions

The increasing interest in the functional versatility of glycan epitopes in cellular glycoconjugates calls for developing sensitive methods to define carbohydrate conformation in solution and to characterize protein–carbohydrate interactions. Measurements of pseudocontact shifts in the presence of a...

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Veröffentlicht in:	Journal of the American Chemical Society 2014-06, Vol.136 (22), p.8011-8017
Hauptverfasser:	Canales, Ángeles, Mallagaray, Álvaro, Berbís, M. Álvaro, Navarro-Vázquez, Armando, Domínguez, Gema, Cañada, F. Javier, André, Sabine, Gabius, Hans-Joachim, Pérez-Castells, Javier, Jiménez-Barbero, Jesús
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrate Conformation Carbohydrate Sequence Carbohydrates - chemistry Chelating Agents - chemistry Disaccharides - chemistry Electron Spin Resonance Spectroscopy Galectin 3 - chemistry Glycoconjugates - metabolism Lactose - chemistry Lanthanoid Series Elements - chemistry Polysaccharides - chemistry Proteins - chemistry
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