Abolition of anti-adhesiogenic effect of heparin by protamine sulfate

Abstract Objective Intraabdominal adhesion is a frequently encountered condition after surgery and can end up in important complications. The objective of this study is to test whether the antiadhesiogenic effect of heparin could be antagonized by administration of protamine in a rat model. Material...

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Veröffentlicht in:	International journal of surgery (London, England) England), 2014-01, Vol.12 (7), p.729-733
Hauptverfasser:	Reyhan, Enver, İrkörücü, Oktay, Sürmelioğlu, Ali, Özkara, Selvinaz, Değer, Kamuran Cumhur, Aziret, Mehmet, Erdem, Hasan, Çetinkünar, Süleyman, Tilki, Metin, Demirtürk, Pelin, Akpinar, Edip
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Animals Anticoagulant Antidote Antithrombine Disease Models, Animal Female Fibrinolytic Agents - administration & dosage Fibrosis - etiology Fibrosis - pathology Fibrosis - prevention & control Heparin - administration & dosage Inflammation - etiology Inflammation - pathology Inflammation - prevention & control Laparotomy - adverse effects Neovascularization, Pathologic - etiology Neovascularization, Pathologic - pathology Neovascularization, Pathologic - prevention & control Protamine sulfate Protamines - administration & dosage Protamines - adverse effects Rats Rats, Wistar Surgery Tissue Adhesions - etiology Tissue Adhesions - pathology Tissue Adhesions - prevention & control
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