BDNF Val66Met modifies the risk of childhood trauma on obsessive-compulsive disorder

Abstract Childhood trauma has been linked to the development of later psychopathology, including obsessive-compulsive disorder (OCD). Although evidence exists to suggest that genetic and environmental factors are involved in the aetiology of OCD, little attention has been paid to the interactions th...

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Veröffentlicht in:	Journal of psychiatric research 2013-12, Vol.47 (12), p.1857-1863
Hauptverfasser:	Hemmings, Sian Megan Joanna, Lochner, Christine, van der Merwe, Lize, Cath, Danielle C, Seedat, Soraya, Stein, Dan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adult and adolescent clinical studies Aged Anxiety disorders. Neuroses Biological and medical sciences Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - genetics Child Child Abuse - psychology Childhood abuse Childhood trauma CTQ Emotional abuse Environmental aspects Female Gene-Environment Interaction Genes Genetic Predisposition to Disease Genotype Humans Linear Models Male Medical sciences Methionine - genetics Middle Aged Obsessive-compulsive disorder (OCD) Obsessive-Compulsive Disorder - etiology Obsessive-Compulsive Disorder - genetics Obsessive-compulsive disorders Obsessive-Compulsive neuroses Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology Psychopathology. Psychiatry Surveys and Questionnaires Valine - genetics Young Adult
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