Overreplication of the Origin Region in the dnaB37 Mutant of Bacillus subtilis: Postinitiation Control of Chromosomal Replication

When the Bacillus subtilis dnaB37 mutant, defective in initiation, is returned to permissive temperature after accumulation of initiation proteins at 45 degrees C, we have shown, by extensive DNA· DNA hybridization analysis, that the origin region is replicated in excess (≈ 2-fold). However, this re...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1989-11, Vol.86 (22), p.8660-8664
Hauptverfasser:	Henckes, Gilles, Harper, Francis, Levine, Alain, Vannier, Françoise, Séror, Simone J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis - genetics Bacteria Bacterial Proteins - genetics Biological and medical sciences Chromosomes Chromosomes, Bacterial - physiology DNA DNA probes DNA Replication DNA, Bacterial - genetics DNA, Bacterial - ultrastructure Fundamental and applied biological sciences. Psychology Kinetics Molecular and cellular biology Molecular genetics Mutation Nucleic acids Plasmids Protein Biosynthesis Replication Replication origin RNA
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