Immune stimulatory properties of metalloporphyrins

A possible approach to the immunotherapy of tumors is to stimulate either specific or nonspecific immune responses in vivo. We recently found that provision of a mitogenic signal to PBMC, by incubation with the oxidizing mitogens, enhanced the effect of IL-2 in generating cytolytic activity. We ther...

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Veröffentlicht in:	The Journal of immunology (1950) 1989-12, Vol.143 (12), p.3981-3987
Hauptverfasser:	Novogrodsky, A, Suthanthiran, M, Stenzel, KH
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Adult Antigens, Surface - analysis Hemin - pharmacology Humans Interferon-gamma - biosynthesis Lymphocyte Activation - drug effects Metalloporphyrins - pharmacology Middle Aged Mitogens - pharmacology Tumor Necrosis Factor-alpha - biosynthesis
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