Locus Specificity for Mutation Induction in Human Cells Exposed to Accelerated Heavy Ions

Summary The relative efficiencies of two types of densely ionizing particles were compared for the induction of mutations at two distinct genetic loci in human cells. Mutations to 6-thioguanine resistance (hgprt locus) or to trifluorothymidine resistance (tk) locus were scored in TK6 human lymphobla...

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Veröffentlicht in:International journal of radiation biology 1989, Vol.55 (6), p.913-924
Hauptverfasser: Kronenberg, A., Little, J.B.
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Sprache:eng
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