Multivalent agents containing 1-substituted 2,3,4-trihydroxyphenyl moieties as novel synthetic polyphenols directed against HIV-1

The synthesis and the assessment of the anti-HIV activity of a set of molecules inspired by the multivalent structures of some naturally-occurring polyphenols (tannins) are reported. Different multibranched scaffolds have been derived from pentaerythritol as the central core which distribute spatial...

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Veröffentlicht in:Organic & biomolecular chemistry 2014-07, Vol.12 (28), p.5278-5294
Hauptverfasser: Flores, Aida, Camarasa, María José, Pérez-Pérez, María Jesús, San-Félix, Ana, Balzarini, Jan, Quesada, Ernesto
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Sprache:eng
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