A Palindromic CpG-Containing Phosphodiester Oligodeoxynucleotide as a Mucosal Adjuvant Stimulates Plasmacytoid Dendritic Cell-Mediated TH1 Immunity: e88846

Background CpG oligodeoxynucleotides (ODNs), resembling bacterial DNA, are currently tested in clinical trials as vaccine adjuvants. They have the nuclease-resistant phosphorothioate bond; the immune responses elicited differ according to the CpG ODN sequence and vaccination method. To develop a CpG...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2)
Hauptverfasser:	Maeyama, Jun-ichi, Takatsuka, Hisakazu, Suzuki, Fumiko, Kubota, Ayumi, Horiguchi, Satomi, Komiya, Takako, Shimada, Ichiroh, Murata, Eri, Osawa, Youko, Kitagawa, Harukazu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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