Homeostatic control of regulatory T cell diversity

Key Points Regulatory T (T Reg ) cells can be induced in both the thymus and the periphery. Together, these T Reg cells constitute the peripheral T Reg cell pool, which can be divided into 'central' T Reg cells, 'effector' T Reg cells and 'tissue-resident' T Reg cells....

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Veröffentlicht in:	Nature reviews. Immunology 2014-03, Vol.14 (3), p.154-165
Hauptverfasser:	Liston, Adrian, Gray, Daniel H. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/1619/554/1898/1271 Animals Antigens Apoptosis Apoptosis - immunology B-cell lymphoma BIM protein Biological diversity Biomedicine Cell death Cell division Cell Division - immunology Cell Proliferation Cell size Cytokines Effector cells Forkhead protein Forkhead Transcription Factors - metabolism Foxp3 protein Graft-versus-host reaction Heterogeneity Homeostasis Homeostasis - immunology Humans Immune response Immunology Inflammation - immunology Interleukin 2 Leukemia Lymphocytes B Lymphocytes T Lymphoid tissue Lymphoma Mcl-1 protein Medical research Medicine, Experimental Mice Microenvironments Phenotypic plasticity Phosphorylation Physiological aspects Population number review-article Subpopulations T cells T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology Thymus gland Transcription factors Transcription, Genetic
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