Analysis of the HLA-Cw3-specific cytotoxic T lymphocyte response of HLA- B7 X human beta 2m double transgenic mice

The cytolytic responses of either normal (non transgenic), HLA-B7 (single transgenic) or HLA-B7 x human beta 2 microglobulin (double transgenic) DBA/2 mice induced by transfected HLA-Cw3 P815 (H-2d) mouse mastocytoma cells were compared, to evaluate whether the expression of an HLA class I molecule...

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Veröffentlicht in:	The Journal of immunology (1950) 1989-11, Vol.143 (10), p.3117-3124
Hauptverfasser:	Barra, C, Perarnau, B, Gerlinger, P, Lemeur, M, Gillet, A, Gibier, P, Lemonnier, FA
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Antigens, Ly - immunology beta 2-Microglobulin - genetics beta 2-Microglobulin - immunology Binding, Competitive Cell Separation Clone Cells - analysis Cricetinae Cytotoxicity Tests, Immunologic Epitopes - genetics Epitopes - immunology Gene Rearrangement, T-Lymphocyte H-2 Antigens - genetics H-2 Antigens - immunology HLA-B7 Antigen - genetics HLA-B7 Antigen - immunology HLA-C Antigens - genetics HLA-C Antigens - immunology Humans Lymphocytes - analysis Male Mice Mice, Inbred BALB C Mice, Inbred DBA Mice, Transgenic - genetics Mice, Transgenic - immunology Receptors, Antigen, T-Cell - genetics T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism Thymus Gland - analysis
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