Serratia marcescens harbouring SME-type class A carbapenemases in Canada and the presence of blaSME on a novel genomic island, SmarGI1-1

An increasing prevalence since 2010 of Serratia marcescens harbouring the Ambler class A carbapenemase SME prompted us to further characterize these isolates. Isolates harbouring bla(SME) were identified by PCR and sequencing. Phenotypic analysis for carbapenemase activity was carried out by a modif...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2014-07, Vol.69 (7), p.1825-1829
Hauptverfasser:	Mataseje, L F, Boyd, D A, Delport, J, Hoang, L, Imperial, M, Lefebvre, B, Kuhn, M, Van Caeseele, P, Willey, B M, Mulvey, M R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bacteria Bacterial Proteins - analysis Bacterial Proteins - genetics beta-Lactamases - analysis beta-Lactamases - genetics Canada Disease control DNA, Bacterial - genetics Drug resistance Electrophoresis, Gel, Pulsed-Field Female Gene Transfer, Horizontal Genetic Variation Genomic Islands Genotype & phenotype Humans Interspersed Repetitive Sequences Male Microbial Sensitivity Tests Middle Aged Molecular Sequence Data Molecular Typing Polymerase Chain Reaction Sequence Analysis, DNA Serratia Infections - microbiology Serratia marcescens - enzymology Serratia marcescens - genetics Serratia marcescens - isolation & purification
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