Gastrointestinal Mucositis: The Role of MMP-Tight Junction Interactions in Tissue Injury

Chemotherapy for cancer causes significant gut toxicity known as mucositis. The pathogenesis of mucositis is ill defined. Recent clinical research guidelines have highlighted epithelial junctional complexes as emerging targets within mucositis research. Given the robust biological evidence linking t...

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Veröffentlicht in:	Pathology oncology research 2014-07, Vol.20 (3), p.485-491
Hauptverfasser:	Al-Dasooqi, Noor, Wardill, Hannah R., Gibson, Rachel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cancer Research Gastrointestinal Diseases - metabolism Gastrointestinal Diseases - pathology Humans Immunology Matrix Metalloproteinases - metabolism Mucositis - metabolism Mucositis - pathology Oncology Pathology Review Tight Junctions - metabolism
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