Lipid to protein ratio plays an important role in the skin barrier function in patients with atopic eczema

Summary Background The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE). Filaggrin is an epidermal barrier protein and common mutations...

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