Expression and Regulation of Neuromedin B in Pituitary Corticotrophs of Male Melanocortin 2 Receptor-Deficient Mice

The hypothalamic-pituitary-adrenal (HPA) axis is a major part of the neuroendocrine system that controls responses to stress, and has an important function in the regulation of various body processes. We previously created a mouse line deficient in the melanocortin 2 receptor (MC2R). MC2R-deficient...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2014-07, Vol.155 (7), p.2492-2499
Hauptverfasser:	Kameda, Hiraku, Miyoshi, Hideaki, Shimizu, Chikara, Nagai, So, Nakamura, Akinobu, Kondo, Takuma, Chida, Dai, Atsumi, Tatsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Insufficiency - genetics Adrenal Insufficiency - metabolism Adrenocorticotropic hormone Animals Controlled release Corticosterone Corticosterone - pharmacology Corticotrophs - drug effects Corticotrophs - metabolism Corticotropin-releasing hormone Corticotropin-Releasing Hormone - pharmacology Deoxyribonucleic acid Dexamethasone Dexamethasone - pharmacology DNA DNA chips DNA microarrays Gene expression Gene Expression Profiling Gene Expression Regulation Glucocorticoids Glucocorticoids - pharmacology Hypothalamic-pituitary-adrenal axis Hypothalamus Immunohistochemistry Male Melanocortin Mice Mice, Inbred C57BL Mice, Knockout Neuroendocrine system Neurokinin B - analogs & derivatives Neurokinin B - genetics Neurokinin B - metabolism Neuromedin Oligonucleotide Array Sequence Analysis Pituitary (anterior) Pituitary gland Pituitary Gland - metabolism Polymerase chain reaction Pro-Opiomelanocortin - genetics Pro-Opiomelanocortin - metabolism Proopiomelanocortin Real time Receptor, Melanocortin, Type 2 - genetics Receptor, Melanocortin, Type 2 - metabolism Receptors Reverse Transcriptase Polymerase Chain Reaction
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