Diagnostic value of MPO in patients admitted for suspected acute coronary syndrome--a study of adult in Mostar, Bosnia and Herzegovina
We assessed the diagnostic efficacy of plasma Myeloperoxidasis (MPO) alone or in combination with cardiac troponin I (cTnI) for detecting ACS in patients presenting with chest pain initiating within 24 h before the hospital admission. In this prospective cohort study were included all respondents wh...
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| Veröffentlicht in: | Collegium antropologicum 2014-03, Vol.38 (1), p.213-217 |
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| container_title | Collegium antropologicum |
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| creator | Vasilj, Mirjana Starcević, Boris Volarić, Mile Jelavić, Boris Leventić, Miro Cuk, Danijela Corić, Slavica |
| description | We assessed the diagnostic efficacy of plasma Myeloperoxidasis (MPO) alone or in combination with cardiac troponin I (cTnI) for detecting ACS in patients presenting with chest pain initiating within 24 h before the hospital admission. In this prospective cohort study were included all respondents who have visited outpatient clinic of internal diseases, University Hospital Mostar because of chest pain and suspected acute coronary syndrome within 24 h of the onset of the period of 6 months and the total sample consisted of 114 patients. Troponin and myeloperoxidase were significantly positively correlated at the beginning of treatment, myeloperoxidase was significantly positively associated with adverse cardiovascular events during hospitalization and myocardial infarction (p < 0.05), with the regression analysis did not show a significant predictor in the development of myocardial infarction (p > 0.05). Sensitivity of myeloperoxidase as a valid test detection of myocardial infarction at baseline was 0.15 and specificity was 0.85, suggesting good diagnostic value usable in the clinical practice. |
| format | Article |
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Sensitivity of myeloperoxidase as a valid test detection of myocardial infarction at baseline was 0.15 and specificity was 0.85, suggesting good diagnostic value usable in the clinical practice.</description><identifier>ISSN: 0350-6134</identifier><identifier>PMID: 24851620</identifier><language>eng</language><publisher>Croatia</publisher><subject>Acute Coronary Syndrome - blood ; Acute Coronary Syndrome - diagnosis ; Acute Coronary Syndrome - epidemiology ; Adult ; Adults ; Aged ; Aged, 80 and over ; Biomarkers - blood ; Bosnia and Herzegovina ; Chest Pain - blood ; Chest Pain - diagnosis ; Chest Pain - epidemiology ; Cohort analysis ; Cross-Sectional Studies ; Female ; Heart disease ; Hospital treatment ; Hospitalization ; Humans ; Male ; Medical research ; Middle Aged ; Myocardial Infarction - blood ; Myocardial Infarction - diagnosis ; Myocardial Infarction - epidemiology ; Patients ; Peroxidase - blood ; Risk Factors ; Troponin I - blood ; Young Adult</subject><ispartof>Collegium antropologicum, 2014-03, Vol.38 (1), p.213-217</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24851620$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vasilj, Mirjana</creatorcontrib><creatorcontrib>Starcević, Boris</creatorcontrib><creatorcontrib>Volarić, Mile</creatorcontrib><creatorcontrib>Jelavić, Boris</creatorcontrib><creatorcontrib>Leventić, Miro</creatorcontrib><creatorcontrib>Cuk, Danijela</creatorcontrib><creatorcontrib>Corić, Slavica</creatorcontrib><title>Diagnostic value of MPO in patients admitted for suspected acute coronary syndrome--a study of adult in Mostar, Bosnia and Herzegovina</title><title>Collegium antropologicum</title><addtitle>Coll Antropol</addtitle><description>We assessed the diagnostic efficacy of plasma Myeloperoxidasis (MPO) alone or in combination with cardiac troponin I (cTnI) for detecting ACS in patients presenting with chest pain initiating within 24 h before the hospital admission. In this prospective cohort study were included all respondents who have visited outpatient clinic of internal diseases, University Hospital Mostar because of chest pain and suspected acute coronary syndrome within 24 h of the onset of the period of 6 months and the total sample consisted of 114 patients. Troponin and myeloperoxidase were significantly positively correlated at the beginning of treatment, myeloperoxidase was significantly positively associated with adverse cardiovascular events during hospitalization and myocardial infarction (p < 0.05), with the regression analysis did not show a significant predictor in the development of myocardial infarction (p > 0.05). Sensitivity of myeloperoxidase as a valid test detection of myocardial infarction at baseline was 0.15 and specificity was 0.85, suggesting good diagnostic value usable in the clinical practice.</description><subject>Acute Coronary Syndrome - blood</subject><subject>Acute Coronary Syndrome - diagnosis</subject><subject>Acute Coronary Syndrome - epidemiology</subject><subject>Adult</subject><subject>Adults</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biomarkers - blood</subject><subject>Bosnia and Herzegovina</subject><subject>Chest Pain - blood</subject><subject>Chest Pain - diagnosis</subject><subject>Chest Pain - epidemiology</subject><subject>Cohort analysis</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Heart disease</subject><subject>Hospital treatment</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - blood</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Patients</subject><subject>Peroxidase - blood</subject><subject>Risk Factors</subject><subject>Troponin I - blood</subject><subject>Young Adult</subject><issn>0350-6134</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtOwzAQRbMA0fL4BeQlCyI5duykSyiPIrUqi-6jiT2ujBI72E6l8gF8N60oezZ3dKWjM9I9y6aUC5rLgpeT7DLGD0pFJam8yCasrEUhGZ1m308Wts7HZBXZQTci8Yas3tfEOjJAsuhSJKB7mxJqYnwgcYwDqmMDNSYkygfvIOxJ3DsdfI95DiSmUe-PKtBjl46y1eEHhHvy6KOzQMBpssDwhVu_sw6us3MDXcSb073KNi_Pm_kiX65f3-YPy3yoZzQvsTXMVFyrWmIpkCE34hAF1VBopdtWQltIMFxUJYhS8FoxoFgZKksUlF9ld7_aIfjPEWNqehsVdh049GNsCsElpTNZ8X-grOZcspod0NsTOrY96mYItj8M0vytzH8ANW55UQ</recordid><startdate>201403</startdate><enddate>201403</enddate><creator>Vasilj, Mirjana</creator><creator>Starcević, Boris</creator><creator>Volarić, Mile</creator><creator>Jelavić, Boris</creator><creator>Leventić, Miro</creator><creator>Cuk, Danijela</creator><creator>Corić, Slavica</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope></search><sort><creationdate>201403</creationdate><title>Diagnostic value of MPO in patients admitted for suspected acute coronary syndrome--a study of adult in Mostar, Bosnia and Herzegovina</title><author>Vasilj, Mirjana ; 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In this prospective cohort study were included all respondents who have visited outpatient clinic of internal diseases, University Hospital Mostar because of chest pain and suspected acute coronary syndrome within 24 h of the onset of the period of 6 months and the total sample consisted of 114 patients. Troponin and myeloperoxidase were significantly positively correlated at the beginning of treatment, myeloperoxidase was significantly positively associated with adverse cardiovascular events during hospitalization and myocardial infarction (p < 0.05), with the regression analysis did not show a significant predictor in the development of myocardial infarction (p > 0.05). Sensitivity of myeloperoxidase as a valid test detection of myocardial infarction at baseline was 0.15 and specificity was 0.85, suggesting good diagnostic value usable in the clinical practice.</abstract><cop>Croatia</cop><pmid>24851620</pmid><tpages>5</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnosis Acute Coronary Syndrome - epidemiology Adult Adults Aged Aged, 80 and over Biomarkers - blood Bosnia and Herzegovina Chest Pain - blood Chest Pain - diagnosis Chest Pain - epidemiology Cohort analysis Cross-Sectional Studies Female Heart disease Hospital treatment Hospitalization Humans Male Medical research Middle Aged Myocardial Infarction - blood Myocardial Infarction - diagnosis Myocardial Infarction - epidemiology Patients Peroxidase - blood Risk Factors Troponin I - blood Young Adult |
| title | Diagnostic value of MPO in patients admitted for suspected acute coronary syndrome--a study of adult in Mostar, Bosnia and Herzegovina |
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