A MicroRNA Cluster at 14q32 Drives Aggressive Lung Adenocarcinoma

To determine whether different subtypes of lung adenocarcinoma (AC) have distinct microRNA (miRNA) expression profiles, and to identify miRNAs associated with aggressive subgroups of resected lung AC. miRNA expression profile analysis was performed in 91 resected lung AC and 10 matched nonmalignant...

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Veröffentlicht in:	Clinical cancer research 2014-06, Vol.20 (12), p.3107-3117
Hauptverfasser:	NADAL, Ernest, JINJIE ZHONG, LIN, Jules, REDDY, Rishindra M, RAMNATH, Nithya, ORRINGER, Mark B, CHANG, Andrew C, BEER, David G, GUOAN CHEN
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Mucinous - genetics Adenocarcinoma, Mucinous - mortality Adenocarcinoma, Mucinous - secondary Aged Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - genetics Carcinoma, Papillary - genetics Carcinoma, Papillary - mortality Carcinoma, Papillary - secondary Case-Control Studies Cell Movement Chromosomes, Human, Pair 14 - genetics Cluster Analysis Cohort Studies Female Follow-Up Studies Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Silencing Humans Lung - metabolism Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Lymphatic Metastasis Male Medical sciences MicroRNAs - genetics Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Invasiveness Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging Pharmacology. Drug treatments Pneumology Prognosis Survival Rate Tumor Cells, Cultured Tumors Tumors of the respiratory system and mediastinum
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