Characterization of a Novel Peptide Toxin from Acanthoscurria paulensis Spider Venom: A Distinct Cysteine Assignment to the HWTX-II Family

Spider venom toxins have raised interest in prospecting new drugs and pesticides. Nevertheless, few studies are conducted with tarantula toxins, especially with species found in Brazil. This study aims to characterize chemically and biologically the first toxin isolated from Acanthoscurria paulensis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2013-04, Vol.52 (14), p.2440-2452
Hauptverfasser:	Mourão, Caroline B. F, Heghinian, Mari D, Barbosa, Eder A, Marí, Frank, Bloch, Carlos, Restano-Cassulini, Rita, Possani, Lourival D, Schwartz, Elisabeth F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Araneae Cysteine - chemistry Drosophila melanogaster Female HEK293 Cells Humans Insecta - drug effects Male Mice Molecular Sequence Data Paralysis - chemically induced Peptides - chemistry Peptides - isolation & purification Peptides - pharmacology Peptides - toxicity Protein Structure, Secondary Receptors, Nicotinic - metabolism Spider Venoms - chemistry Spider Venoms - isolation & purification Spider Venoms - pharmacology Spider Venoms - toxicity Spiders - chemistry Spodoptera frugiperda Voltage-Gated Sodium Channels - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!