Copy number variant study of bipolar disorder in Canadian and UK populations implicates synaptic genes

Genome‐wide single nucleotide polymorphism (SNP) data from 936 bipolar disorder (BD) individuals and 940 psychiatrically healthy comparison individuals of North European descent were analyzed for copy number variation (CNV). Using multiple CNV calling algorithms, and validating using in vitro molecu...

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Veröffentlicht in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Neuropsychiatric genetics, 2014-06, Vol.165B (4), p.303-313
Hauptverfasser:	Noor, Abdul, Lionel, Anath C., Cohen-Woods, Sarah, Moghimi, Narges, Rucker, James, Fennell, Alanna, Thiruvahindrapuram, Bhooma, Kaufman, Liana, Degagne, Bryan, Wei, John, Parikh, Sagar V., Muglia, Pierandrea, Forte, Julia, Scherer, Stephen W., Kennedy, James L., Xu, Wei, McGuffin, Peter, Farmer, Anne, Strauss, John, Vincent, John B.
Format:	Artikel
Sprache:	eng
Schlagworte:	bipolar disorder Bipolar Disorder - genetics Canada Case-Control Studies Cell Adhesion Molecules, Neuronal - genetics copy number variant DNA Copy Number Variations - genetics Genetics Humans Nerve Tissue Proteins - genetics NRXN1 Reproducibility of Results synapse Synapses - genetics United Kingdom Young Adult
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