Relevance of Lysine Snorkeling in the Outer Transmembrane Domain of Small Viral Potassium Ion Channels

Transmembrane domains (TMDs) are often flanked by Lys or Arg because they keep their aliphatic parts in the bilayer and their charged groups in the polar interface. Here we examine the relevance of this so-called “snorkeling” of a cationic amino acid, which is conserved in the outer TMD of small vir...

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Veröffentlicht in:Biochemistry (Easton) 2012-07, Vol.51 (28), p.5571-5579
Hauptverfasser: Gebhardt, Manuela, Henkes, Leonhard M, Tayefeh, Sascha, Hertel, Brigitte, Greiner, Timo, Van Etten, James L, Baumeister, Dirk, Cosentino, Cristian, Moroni, Anna, Kast, Stefan M, Thiel, Gerhard
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Sprache:eng
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