A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb Proteins: e95216

Long noncoding RNAs (lncRNAs) have emerged as a major regulator of cell physiology, but many of which have no known function. CDKN1A/p21 is an important inhibitor of the cell-cycle, regulator of the DNA damage response and effector of the tumor suppressor p53, playing a crucial role in tumor develop...

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Veröffentlicht in:	PloS one 2014-04, Vol.9 (4)
Hauptverfasser:	Negishi, Masamitsu, Wongpalee, Somsakul P, Sarkar, Sukumar, Park, Jonghoon, Lee, Kyung Yong, Shibata, Yoshiyuki, Reon, Brian J, Abounader, Roger, Suzuki, Yutaka, Sugano, Sumio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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