Selection of Rodent Species Appropriate for mtDNA Transfer to Generate Transmitochondrial Mito-Mice Expressing Mitochondrial Respiration Defects

Previous reports have shown that transmitochondrial mito-mice with nuclear DNA from Mus musculus and mtDNA from M. spretus do not express respiration defects, whereas those with mtDNA from Rattus norvegicus cannot be generated from ES cybrids with mtDNA from R. norvegicus due to inducing significant...

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Veröffentlicht in:	Experimental Animals 2014, Vol.63(1), pp.21-30
Hauptverfasser:	Enoki, Shunkei, Shimizu, Akinori, Hayashi, Chisato, Imanishi, Hirotake, Hashizume, Osamu, Mekada, Kazuyuki, Suzuki, Hitoshi, Hashimoto, Tetsuo, Nakada, Kazuto, Hayashi, Jun-Ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	interspecies mtDNA transfer multipotency Mus caroli mtDNA Mus musculus Rattus norvegicus respiration defects transmitochondrial ES cybrids
Online-Zugang:	Volltext
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