Polymorphisms of endothelin 1 (G5665T and T-1370G) and endothelin receptor type A (C+70G and G-231A) in Graves' disease

Endothelin 1 (EDN1) is a strong angiogenic and mitogenic factor, playing a key role in hypervascularization, thyroid follicle cell hyperplasia, and lymphocyte infiltration in the thyroid gland of patients with Graves’ disease (GD). EDN1 induces angiogenesis and mitogenesis via endothelin receptor ty...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International immunopharmacology 2014-01, Vol.18 (1), p.198-202
Hauptverfasser:	Aydın, A. Fatih, Develi-İş, Seval, Doğru-Abbasoğlu, Semra, Vural, Pervin, Özderya, Ayşenur, Karadağ, Berrin, Uysal, Müjdat
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Angiogenesis Antibody Formation - genetics Autoantibodies - blood Autoantibody DNA Mutational Analysis Endothelin family Endothelin-1 - metabolism Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype Graves Disease - complications Graves Disease - genetics Graves Ophthalmopathy - etiology Graves Ophthalmopathy - genetics Graves' disease Humans Male Middle Aged Ophthalmopathy Polymorphism Polymorphism, Single Nucleotide Receptor, Endothelin A - genetics Receptor, Endothelin A - metabolism Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!