The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms
Synopsis Objective We review the relationship between vitamin D and seborrhoeic keratosis (SK). Methods Review literature from MEDLINE. Results Vitamin D3 supplementation can improve SK lesions. Genetics‐based studies have identified the proteins that link vitamin D to SK pathology. Vitamin D also e...
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| Veröffentlicht in: | International journal of cosmetic science 2013-12, Vol.35 (6), p.525-531 |
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| container_title | International journal of cosmetic science |
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| creator | Luong, Kvq Nguyen, LTH |
| description | Synopsis
Objective
We review the relationship between vitamin D and seborrhoeic keratosis (SK).
Methods
Review literature from MEDLINE.
Results
Vitamin D3 supplementation can improve SK lesions. Genetics‐based studies have identified the proteins that link vitamin D to SK pathology. Vitamin D also exerts its effect on SK through cell signalling mechanisms.
Conclusion
Vitamin D plays a role in SK. Calcitriol is the best form of vitamin D for use in patients with SK because it is the active form of the vitamin D3 metabolite and its receptors are present in the skin. Further investigation of the effects of calcitriol in patients with SK is warranted.
Résumé
Objectif
nous examinons la relation entre la vitamine D et la kératose séborrhéique (SK).
Méthodes
revue de la littérature à partir de Medline.
Résultats
la supplémentation en vitamine D3 peut améliorer les lésions SK. Des études des bases de données génétiques ont identifié des protéines qui lient la vitamine D à la pathologie SK. La vitamine D exerce également son effet sur SK grâce à des mécanismes de signalisation cellulaire.
Conclusion
La vitamine D peut jouer un rôle dans SK. Le calcitriol est la meilleure forme de vitamine D chez les patients SK parce que c'est la forme active du métabolite de la vitamine D3 et ses récepteurs sont présents dans la peau. Une enquête plus poussée des effets de calcitriol chez les patients SK est justifiée. |
| doi_str_mv | 10.1111/ics.12080 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1534844026</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1467636472</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4590-28a9af2865ac67e3a0c83abf675b74116ac5e7672b7351e26daf727fd1e472b83</originalsourceid><addsrcrecordid>eNqFkc1u1DAURi0EokNhwQsgS2xgkdb_TtihAUqlESxa2u4sx7mZcevEg50AfXs8TNsFEsILW7LPPfK9H0IvKTmiZR17l48oIzV5hBZUqLpiohGP0YJQwSopFD9Az3K-JoSIpuZP0QHjtWwo1wvUnW8Apxgg49jjH36ygx_xB1y2DG1MaRPBO3wDyU4x-_wOb2POvg2A1zDCVN7s2GEHIczBJpz9erQh-HGNB3AbO_o85OfoSW9Dhhd35yH69unj-fJztfp6crp8v6qckA2pWG0b27NaSeuUBm6Jq7lte6VlqwWlyjoJWmnWai4pMNXZXjPddxREuaz5IXqz925T_D5Dnszg8-5rdoQ4Z0MlF7UQhKn_o0JpxVXxFvT1X-h1nFPpckcVrFGUiEK93VMulQEl6M02-cGmW0OJ2aVkSkrmT0qFfXVnnNsBugfyPpYCHO-Bnz7A7b9N5nR5dq-s9hU-T_DrocKmG6M019JcfjkxqyvGLy6vzswF_w1Dmao-</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1446796104</pqid></control><display><type>article</type><title>The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Luong, Kvq ; Nguyen, LTH</creator><creatorcontrib>Luong, Kvq ; Nguyen, LTH</creatorcontrib><description>Synopsis
Objective
We review the relationship between vitamin D and seborrhoeic keratosis (SK).
Methods
Review literature from MEDLINE.
Results
Vitamin D3 supplementation can improve SK lesions. Genetics‐based studies have identified the proteins that link vitamin D to SK pathology. Vitamin D also exerts its effect on SK through cell signalling mechanisms.
Conclusion
Vitamin D plays a role in SK. Calcitriol is the best form of vitamin D for use in patients with SK because it is the active form of the vitamin D3 metabolite and its receptors are present in the skin. Further investigation of the effects of calcitriol in patients with SK is warranted.
Résumé
Objectif
nous examinons la relation entre la vitamine D et la kératose séborrhéique (SK).
Méthodes
revue de la littérature à partir de Medline.
Résultats
la supplémentation en vitamine D3 peut améliorer les lésions SK. Des études des bases de données génétiques ont identifié des protéines qui lient la vitamine D à la pathologie SK. La vitamine D exerce également son effet sur SK grâce à des mécanismes de signalisation cellulaire.
Conclusion
La vitamine D peut jouer un rôle dans SK. Le calcitriol est la meilleure forme de vitamine D chez les patients SK parce que c'est la forme active du métabolite de la vitamine D3 et ses récepteurs sont présents dans la peau. Une enquête plus poussée des effets de calcitriol chez les patients SK est justifiée.</description><identifier>ISSN: 0142-5463</identifier><identifier>EISSN: 1468-2494</identifier><identifier>DOI: 10.1111/ics.12080</identifier><identifier>PMID: 23859137</identifier><identifier>CODEN: IJCMDW</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>calcitriol ; Humans ; Keratosis, Seborrheic - genetics ; Keratosis, Seborrheic - metabolism ; seborrhoeic keratosis ; seborrhoeic solaris ; senile warts ; Vitamin D ; Vitamin D - metabolism</subject><ispartof>International journal of cosmetic science, 2013-12, Vol.35 (6), p.525-531</ispartof><rights>2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie</rights><rights>2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie.</rights><rights>Copyright © 2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4590-28a9af2865ac67e3a0c83abf675b74116ac5e7672b7351e26daf727fd1e472b83</citedby><cites>FETCH-LOGICAL-c4590-28a9af2865ac67e3a0c83abf675b74116ac5e7672b7351e26daf727fd1e472b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fics.12080$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fics.12080$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23859137$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Luong, Kvq</creatorcontrib><creatorcontrib>Nguyen, LTH</creatorcontrib><title>The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms</title><title>International journal of cosmetic science</title><addtitle>Int J Cosmet Sci</addtitle><description>Synopsis
Objective
We review the relationship between vitamin D and seborrhoeic keratosis (SK).
Methods
Review literature from MEDLINE.
Results
Vitamin D3 supplementation can improve SK lesions. Genetics‐based studies have identified the proteins that link vitamin D to SK pathology. Vitamin D also exerts its effect on SK through cell signalling mechanisms.
Conclusion
Vitamin D plays a role in SK. Calcitriol is the best form of vitamin D for use in patients with SK because it is the active form of the vitamin D3 metabolite and its receptors are present in the skin. Further investigation of the effects of calcitriol in patients with SK is warranted.
Résumé
Objectif
nous examinons la relation entre la vitamine D et la kératose séborrhéique (SK).
Méthodes
revue de la littérature à partir de Medline.
Résultats
la supplémentation en vitamine D3 peut améliorer les lésions SK. Des études des bases de données génétiques ont identifié des protéines qui lient la vitamine D à la pathologie SK. La vitamine D exerce également son effet sur SK grâce à des mécanismes de signalisation cellulaire.
Conclusion
La vitamine D peut jouer un rôle dans SK. Le calcitriol est la meilleure forme de vitamine D chez les patients SK parce que c'est la forme active du métabolite de la vitamine D3 et ses récepteurs sont présents dans la peau. Une enquête plus poussée des effets de calcitriol chez les patients SK est justifiée.</description><subject>calcitriol</subject><subject>Humans</subject><subject>Keratosis, Seborrheic - genetics</subject><subject>Keratosis, Seborrheic - metabolism</subject><subject>seborrhoeic keratosis</subject><subject>seborrhoeic solaris</subject><subject>senile warts</subject><subject>Vitamin D</subject><subject>Vitamin D - metabolism</subject><issn>0142-5463</issn><issn>1468-2494</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAURi0EokNhwQsgS2xgkdb_TtihAUqlESxa2u4sx7mZcevEg50AfXs8TNsFEsILW7LPPfK9H0IvKTmiZR17l48oIzV5hBZUqLpiohGP0YJQwSopFD9Az3K-JoSIpuZP0QHjtWwo1wvUnW8Apxgg49jjH36ygx_xB1y2DG1MaRPBO3wDyU4x-_wOb2POvg2A1zDCVN7s2GEHIczBJpz9erQh-HGNB3AbO_o85OfoSW9Dhhd35yH69unj-fJztfp6crp8v6qckA2pWG0b27NaSeuUBm6Jq7lte6VlqwWlyjoJWmnWai4pMNXZXjPddxREuaz5IXqz925T_D5Dnszg8-5rdoQ4Z0MlF7UQhKn_o0JpxVXxFvT1X-h1nFPpckcVrFGUiEK93VMulQEl6M02-cGmW0OJ2aVkSkrmT0qFfXVnnNsBugfyPpYCHO-Bnz7A7b9N5nR5dq-s9hU-T_DrocKmG6M019JcfjkxqyvGLy6vzswF_w1Dmao-</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Luong, Kvq</creator><creator>Nguyen, LTH</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><scope>RC3</scope></search><sort><creationdate>201312</creationdate><title>The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms</title><author>Luong, Kvq ; Nguyen, LTH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4590-28a9af2865ac67e3a0c83abf675b74116ac5e7672b7351e26daf727fd1e472b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>calcitriol</topic><topic>Humans</topic><topic>Keratosis, Seborrheic - genetics</topic><topic>Keratosis, Seborrheic - metabolism</topic><topic>seborrhoeic keratosis</topic><topic>seborrhoeic solaris</topic><topic>senile warts</topic><topic>Vitamin D</topic><topic>Vitamin D - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luong, Kvq</creatorcontrib><creatorcontrib>Nguyen, LTH</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Genetics Abstracts</collection><jtitle>International journal of cosmetic science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luong, Kvq</au><au>Nguyen, LTH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms</atitle><jtitle>International journal of cosmetic science</jtitle><addtitle>Int J Cosmet Sci</addtitle><date>2013-12</date><risdate>2013</risdate><volume>35</volume><issue>6</issue><spage>525</spage><epage>531</epage><pages>525-531</pages><issn>0142-5463</issn><eissn>1468-2494</eissn><coden>IJCMDW</coden><abstract>Synopsis
Objective
We review the relationship between vitamin D and seborrhoeic keratosis (SK).
Methods
Review literature from MEDLINE.
Results
Vitamin D3 supplementation can improve SK lesions. Genetics‐based studies have identified the proteins that link vitamin D to SK pathology. Vitamin D also exerts its effect on SK through cell signalling mechanisms.
Conclusion
Vitamin D plays a role in SK. Calcitriol is the best form of vitamin D for use in patients with SK because it is the active form of the vitamin D3 metabolite and its receptors are present in the skin. Further investigation of the effects of calcitriol in patients with SK is warranted.
Résumé
Objectif
nous examinons la relation entre la vitamine D et la kératose séborrhéique (SK).
Méthodes
revue de la littérature à partir de Medline.
Résultats
la supplémentation en vitamine D3 peut améliorer les lésions SK. Des études des bases de données génétiques ont identifié des protéines qui lient la vitamine D à la pathologie SK. La vitamine D exerce également son effet sur SK grâce à des mécanismes de signalisation cellulaire.
Conclusion
La vitamine D peut jouer un rôle dans SK. Le calcitriol est la meilleure forme de vitamine D chez les patients SK parce que c'est la forme active du métabolite de la vitamine D3 et ses récepteurs sont présents dans la peau. Une enquête plus poussée des effets de calcitriol chez les patients SK est justifiée.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>23859137</pmid><doi>10.1111/ics.12080</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | International journal of cosmetic science, 2013-12, Vol.35 (6), p.525-531 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | calcitriol Humans Keratosis, Seborrheic - genetics Keratosis, Seborrheic - metabolism seborrhoeic keratosis seborrhoeic solaris senile warts Vitamin D Vitamin D - metabolism |
| title | The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms |
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