Glatiramer Acetate (Copaxone) Modulates Platelet Activation and Inhibits Thrombin-Induced Calcium Influx: Possible Role of Copaxone in Targeting Platelets during Autoimmune Neuroinflammation: e96256

Background Glatiramer acetate (GA, Copaxone, Copolymer-1) is an FDA approved drug for the treatment of MS and it is very effective in suppressing neuroinflammation in experimental autoimmune encephalitis (EAE), an animal model of MS. Although this drug was designed to inhibit pathogenic T cells, the...

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Veröffentlicht in:PloS one 2014-05, Vol.9 (5)
Hauptverfasser: Starossom, Sarah C, Veremeyko, Tatyana, Dukhinova, Marina, Yung, Amanda WY, Ponomarev, Eugene D
Format: Artikel
Sprache:eng
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