MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor

MicroRNAs, regulators of messenger RNA translation, have been observed to influence many physiological processes, amongst them the process of aging. Higher levels of microRNA-663 (miR-663) have previously been observed in human dermal fibroblasts subject to both replicative and stress-induced senesc...

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Veröffentlicht in:	Biogerontology (Dordrecht) 2014-06, Vol.15 (3), p.269-278
Hauptverfasser:	Waaijer, Mariëtte E. C., Wieser, Matthias, Grillari-Voglauer, Regina, van Heemst, Diana, Grillari, Johannes, Maier, Andrea B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Aging Aging - genetics Aging - metabolism Apoptosis - genetics Apoptosis - physiology Biobanks Biomedical and Life Sciences Biopsy Biotechnology Cell Biology Cells, Cultured Cellular Senescence - genetics Cellular Senescence - physiology Dermis - cytology Developmental Biology Female Fibroblasts - cytology Fibroblasts - metabolism Geriatrics Geriatrics/Gerontology Gerontology Humans Life Sciences Male MicroRNAs MicroRNAs - metabolism Middle age Middle Aged Oxidative stress Oxidative Stress - genetics Physiology Research Article Senescence White people Young Adult
Online-Zugang:	Volltext
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