Modulation of cardiac mitochondrial permeability transition and apoptotic signaling by endurance training and intermittent hypobaric hypoxia

Abstract Background Modulation of the mitochondrial permeability transition pore (MPTP) and inhibition of the apoptotic signaling are critically associated with the cardioprotective phenotypes afforded by both intermittent hypobaric-hypoxia (IHH) and endurance-training (ET). We recently proposed tha...

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Veröffentlicht in:	International journal of cardiology 2014-04, Vol.173 (1), p.40-45
Hauptverfasser:	Magalhães, J, Gonçalves, I.O, Lumini-Oliveira, J, Marques-Aleixo, I, Passos, E, Rocha-Rodrigues, S, Machado, N.G, Moreira, A.C, Rizo, D, Viscor, G, Oliveira, P.J, Torrella, J.R, Ascensão, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Altitude Animals Apoptosis Apoptosis - physiology Biological and medical sciences Cardiology. Vascular system Cardioprotection Cardiovascular Heart Hypoxia - metabolism Male Medical sciences Mitochondria, Heart - physiology Mitochondrial Membrane Transport Proteins - physiology Oxidative damage Oxidative Stress - physiology Physical Conditioning, Animal - methods Physical Conditioning, Animal - physiology Physical exercise Rats Rats, Wistar Signal Transduction - physiology
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