Valeriana officinalis extract and its main component, valerenic acid, ameliorate d-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation

Valeriana officinalis is used in herbal medicine of many cultures as mild sedatives and tranquilizers. In this study, we investigated the effects of extract from valerian root extracts and its major component, valerenic acid on memory function, cell proliferation, neuroblast differentiation, serum c...

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Veröffentlicht in:	Experimental gerontology 2013-11, Vol.48 (11), p.1369-1377
Hauptverfasser:	Nam, Sung Min, Choi, Jung Hoon, Yoo, Dae Young, Kim, Woosuk, Jung, Hyo Young, Kim, Jong Whi, Kang, Soo-Yong, Park, Jaeil, Kim, Dong-Woo, Kim, Wan Jae, Yoon, Yeo Sung, Hwang, In Koo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - metabolism Aging - pathology Aging - psychology Animals Cell Differentiation - drug effects Cell Proliferation - drug effects Corticosterone - blood Dentate Gyrus - cytology Dentate Gyrus - drug effects Dentate Gyrus - metabolism Galactose - pharmacology Hippocampus Indenes - pharmacology Lipid peroxidation Lipid Peroxidation - drug effects Male Memory - drug effects Mice Mice, Inbred C57BL Neural Stem Cells - cytology Neural Stem Cells - drug effects Neurogenesis Neurogenesis - drug effects Neurogenesis - physiology Nootropic Agents - pharmacology Plant Extracts - pharmacology Plants, Medicinal - chemistry Serum corticosterone Sesquiterpenes - pharmacology Valerian - chemistry Valerian root extract Valeriana officinalis
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