effects of p38 gene silencing on breast cancer cells

p38 mitogen-activated protein kinases (MAPK) are members of the MAPK family that are activated by inflammatory cytokines and a variety of environmental stresses. It mediates various biological processes. p38 MAPK activity play important roles in tumour progression. Excessive p38 expression is observ...

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Veröffentlicht in:	Molecular biology reports 2014-05, Vol.41 (5), p.2923-2927
Hauptverfasser:	Doğaner, Fulya, Turgut Coşan, Didem, Güneş, Hasan Veysi, Değirmenci, Irfan, Bal, Cengiz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Animals Biomedical and Life Sciences Breast cancer breast neoplasms Breast Neoplasms - genetics Breast Neoplasms - metabolism Cell Line, Tumor Cell Proliferation cytokines Enzyme Activation enzyme-linked immunosorbent assay Female Gene Expression Gene Knockdown Techniques Gene Silencing Histology Humans Kinases Life Sciences MCF-7 Cells messenger RNA Mice mitogen-activated protein kinase Morphology NIH 3T3 Cells p38 Mitogen-Activated Protein Kinases - genetics p38 Mitogen-Activated Protein Kinases - metabolism protein synthesis quantitative polymerase chain reaction Ribonucleic acid RNA RNA Interference RNA, Small Interfering - genetics Signal transduction small interfering RNA Transfection
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