The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation

Receptors expressed on the growth cone of outgrowing axons detect cues required for proper navigation. The pathway choices available to an axon are in part defined by the set of guidance receptors present on the growth cone. Regulated expression of receptors and genes controlling the localization an...

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Veröffentlicht in:	Developmental biology 2013-05, Vol.377 (2), p.385-398
Hauptverfasser:	Steimel, Andreas, Suh, Jinkyo, Hussainkhel, Angela, Deheshi, Samineh, Grants, Jennifer M., Zapf, Richard, Moerman, Donald G., Taubert, Stefan, Hutter, Harald
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axon guidance Axons - physiology C. elegans Caenorhabditis elegans - embryology CDK8 Cell Movement - physiology Cyclin-Dependent Kinase 8 - metabolism DNA Primers - genetics Gene Expression Profiling Gene Expression Regulation, Developmental Growth Cones - metabolism Mediator Mediator Complex - metabolism Microscopy, Confocal Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nervous System - embryology Neuronal development Receptors, Immunologic - genetics Receptors, Immunologic - metabolism RNA Interference ROBO Roundabout Proteins SAX-3 Transcription
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