[beta]-Sitosterol attenuates high-fat diet-induced intestinal inflammation in mice by inhibiting the binding of lipopolysaccharide to toll-like receptor 4 in the NF-[kappa]B pathway

Scope [beta]-Sitosterol, a common phytosterol, has been shown to exhibit anti-inflammatory effects. Here, we investigated the effect of [beta]-sitosterol on high-fat diet (HFD) induced colitis in mice and on LPS-stimulated mouse intestinal macrophages. Methods and results C57BL/6J mice were maintain...

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Veröffentlicht in:	Molecular nutrition & food research 2014-05, Vol.58 (5), p.963-972
Hauptverfasser:	Kim, Kyung-Ah, Lee, In-Ah, Gu, Wan, Hyam, Supriya R, Kim, Dong-Hyun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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