An innovative biologic recycling process of leukoreduction filters to produce active human antimicrobial peptides

Background Human neutrophil peptides (HNPs) 1 to 3 are the major antimicrobial peptides of the azurophilic granules of neutrophils. They represent an important arm of the innate immune system. Their production by chemical synthesis and recombinant technologies is expensive and limited by technical c...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2014-05, Vol.54 (5), p.1332-1339
Hauptverfasser:	Vossier, Ludivine, Leon, Fanny, Bachelier, Cécile, Marchandin, Hélène, Lehmann, Sylvain, Leonetti, Jean-Paul, Brodolin, Konstantin, Coste, Joliette, Fournier-Wirth, Chantal
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Defensins - isolation & purification alpha-Defensins - pharmacology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Infective Agents - isolation & purification Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Humans Leukocyte Reduction Procedures - methods Medical sciences Microbial Sensitivity Tests Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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