Characterization of the Dynamic Activities of a Population of Microbubbles Driven by Pulsed Ultrasound Exposure in Sonoporation

Abstract Ultrasound-driven microbubble activities have been exploited to transiently disrupt the cell membrane (sonoporation) for non-viral intracellular drug delivery and gene transfection both in vivo and in vitro . In this study, we investigated the dynamic behaviors of a population of microbubbl...

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Veröffentlicht in:	Ultrasound in medicine & biology 2014-06, Vol.40 (6), p.1260-1272
Hauptverfasser:	Fan, Zhenzhen, Chen, Di, Deng, Cheri X
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic radiation force Cavitation Cell Membrane Permeability - physiology Cell Survival Cells, Cultured Contrast Media - pharmacology Equipment Design Fluorocarbons - pharmacology High-speed video microscopy Humans Intracellular delivery Microbubbles Microscopy, Video Radiology Sonication Sonoporation Ultrasound Umbilical Veins - cytology
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