Isolation and some properties of ciguatoxin

Ciguatoxin, the principal toxin of ciguatera produced by a toxic dinoflagellate (Gambierdiscus toxicus ), and accumulated through the food chain in the viscera of moray eels (Gymnothorax javanicus ), was purified. The probable molecular formula C sub(60)H sub(86)O sub(19) was obtained for the first...

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Veröffentlicht in:	Journal of applied phycology 1989-08, Vol.1 (2), p.183-188
Hauptverfasser:	LEGRAND, A. M, LITAUDON, M, GENTHON, J. N, BAGNIS, R, YASUMOTO, T
Format:	Artikel
Sprache:	eng
Schlagworte:	bioaccumulation biochemical composition Biological and medical sciences Chemical constitution chemical extraction ciguatera ciguatoxin food chains Fundamental and applied biological sciences. Psychology Gambierdiscus toxicus Gymnothorax javanicus ISE, French Polynesia Marine mass spectroscopy N.M.R nuclear magnetic resonance Plant physiology and development tissues
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Beschreibung
Zusammenfassung:	Ciguatoxin, the principal toxin of ciguatera produced by a toxic dinoflagellate (Gambierdiscus toxicus ), and accumulated through the food chain in the viscera of moray eels (Gymnothorax javanicus ), was purified. The probable molecular formula C sub(60)H sub(86)O sub(19) was obtained for the first time by high resolution mass spectrometry. super(1)H NMR spectra suggested the presence of a primary hydroxyl group suitable for preparing an antigen necessary to develop an enzyme immunoassay.
ISSN:	0921-8971 1573-5176
DOI:	10.1007/bf00003882