Controversies on the role of 5-HT(2C) receptors in the mechanisms of action of antidepressant drugs

Evidence from the various sources indicates alterations in 5-HT2C receptor functions in anxiety, depression and suicide, and other stress-related disorders treated with antidepressant drugs. Although the notion of a 5-HT2C receptor desensitization following antidepressant treatments is rather well a...

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Veröffentlicht in:	Neuroscience and biobehavioral reviews 2014-05, Vol.42, p.208-223
Hauptverfasser:	Martin, Cedric B P, Hamon, Michel, Lanfumey, Laurence, Mongeau, Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - pharmacology Anxiety - drug therapy Anxiety - physiopathology Brain - drug effects Brain - physiopathology Depressive Disorder - drug therapy Depressive Disorder - physiopathology Humans Receptor, Serotonin, 5-HT2C - metabolism Stress, Psychological - drug therapy Stress, Psychological - physiopathology
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